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LB: That's a grand vision and will get our readers very excited. You just talked about skin aging, hair loss, fat tissue, and these being driven by cellular senescence. This all fits into a bigger picture for longevity technologies over the next decade and more. I think you need to find what makes you happy while also exercising so that you carry on doing it. That's a big thing for me! LB:The discovery of this telomere activating molecule 818 - it has become a fundamental ingredient in your product line. Naturally, we're all very curious. Now we know this is your IP, this is your secret sauce, but what can you tell us about TAM 818? We're fascinated and curious here, Rachael. Glucoside, Cocamidopropyl Hydroxysultaine, Cocamidopropyl Betaine, Dimethyl Sulfone (MSM), Sodium Ascorbyl Phosphate (Vitamin C), Cocamide MIPA, Organic Aloe Barbadensis Leaf Juice (Aloe Vera), Olea Europaea Fruit (Organic Olive) Oil, Rosa Canina Seed (Organic Rosehip Seed) Oil, Borago Officinalis (Borage) Oil, Olea Europaea Fruit (Organic Olive) Oil, Citrus Aurantium Dulcis Extract (Orange Peel) Extract, Origanum Vulgare (Oregano) Extract, Tocopheryl Acetate (Vitamin E), Melaleuca Alternifolia (Tea Tree) Oil. Equisetum Arvense Extract (Horsetail Extract), Taraxacum Officinale Extract (Dandelion Extract), Organic Centella Asiatica Extract (Gotu Kola Extract), Geranium Maculatum Extract (Wild Geranium), Citrus paradisii (Pink grapefruit) oil Phenoxyethanol, Disodium Lauryl Sulfosuccinate, Disodium Laureth Sulfosuccinate, Acrylates/C10- 30 Alkyl Acrylate Crosspolymer, Ethylhexylglycerin. Enhanced with Centella Asiatica, Rosehip Seed Oil, Borage Oil, Orange Peel, Oregano Extract, Vitamin E, Dandelion Extract, Wild Geranium
We are growing human skin in the lab with tissue engineering techniques that myself and my co founders brought from academia. This likely connected to the observable improvements in the overall skin barrier, as discussed in our interview with Carolina.
It’s natural to wonder, what happens after longer term use of OneSkin? Or was the testing a fluke? Could another factor have been in play? LB: That's really a sign of tenacity, as you've just shared and Bill Andrews is clearly a very important figure in the history behind the science and has a relationship with your company. Wrinkles : Wrinkles are furrows, folds or creases in the skin, which increase in occurrence as a result of sun exposure, and are associated with decreasing skin elasticity. This skin feature has the greatest variability from image to image as it is highly dependent upon the facial expression of the client. The Visia scanner was able to highlight the need for me to take much more care with my facial sunscreen routine, and search out proactive solutions for reducing my UV spots. One great option is the Broadband Light (BBL) lasering, which focuses an intense beam of light energy into the skin of the face can destroy these spots and quite literally reverse the age of your skin.
In our interview with OneSkin CEO and Co-Founder Dr. Carolina Reis, we heard about the destructive role of senescent cells in the skin. These aged cells send off inflammatory signals to the surrounding tissue, which extend their impact throughout the body. Namely, extending their health and the function of the skin, more than just acting as a cosmetic (improving only the appearance, focusing on the surface) while we target aging at the molecular level. What is Skinspan? Use on a freshly cleansed face and anytime throughout the day to refresh. Excellent for use over mineral make-up. Particularly given the noted impact of the OS-01 peptide on this parameter in the clinical setting (see image at right).CR:The beauty of this approach is that these models replicate human skin so well, that the results we obtain “in vitro” (in the lab using skin models), will be very similar to the results that were observed in the clinic (in actual human skin).
We've got all these exciting technologies coming up, but at the same time, the fundamentals we already know and understand. HA is a pretty useful tool in terms of skin health – so to our question: How do we know when we're using OS-01 that it's not the hyaluronic acid or other ingredients which are producing the results you claim? How people can be confident the benefits they are seeing are from the OS-01 peptide? Does OneSkin OS-01 Work? Clinical ResultsUV Spots : UV spots occur when melanin coagulates below the skin surface as a result of sun damage. UV spots are generally invisible under normal lighting conditions. As we shift this conversation toward closing out, we are really always very curious to hear how our interview guests look after their own longevity. We call it having your own longevity strategy. Not only does this system provide solid, repeatable quantifiable metrics (pore size, skin redness, texture, etc), but it also is relatively cheap to operate (often a clinic will do this for you for free as a part of a skincare consultation).
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